Skip to content

Glindia

Trimethylchlorosilane

Description

Chlorotrimethylsilane is a silyl chloride consisting of a central silicon atom covalently bound to one chloro and three methyl groups. Chlorotrimethylsilane is a derivatization agent used in gas chromatography/mass spectrometry applications. It has a role as a chromatographic reagent.

Trimethylchlorosilane appears as a colorless fuming liquid with a pungent odor. The vapor and liquid may cause burns. Vapors are heavier than air. It is also used in Remedesvir drug for Novel Coronavirus drug synthesis.

Don't mix this chemical with water
Heat sensitive Chemicals
Ware safety measures while working with this chemicals
Hazardous chemicals
Need care while operating

Category

Pharmaceutical Intermediates

CAS no

75-77-4

Purity

>=99%

Formula

C3H9SiCl

Synonyms

⦁Trimethylsilyl chloride
⦁ Chlorotrimethylsilane
⦁ TMCS
⦁ Monochlorotrimethylsilicon
⦁ Chloro(trimethyl)silane

Form

Liquid

Uses

⦁ In preparation of trimethyl halides, Aldols, pseudohalides, preparation of alkynes, esters, ketones, and aldehydes, also used as a catalyst to increase the reactivity of other silylation reagents. They are also used as a coating for silicon and glass surfaces and in the production of silicone (polysiloxane) polymers.

0