Hydrogen Chloride (HCI) in 1, 4 dioxane (DIOXANE)
Description
Hydrogen Chloride (HCl) in 1,4-Dioxane is a solution of gaseous hydrogen chloride dissolved in 1,4-dioxane, an organic solvent known for its ether-like properties. This solution is used extensively in organic synthesis for acid-catalyzed reactions, including esterification, alkylation, and polymerization. The combination of HCl and 1,4-dioxane creates a stable, non-aqueous medium that enhances reactivity while offering precise control over reaction conditions..
Category
Gas to Liquid Technology - Acids
CAS no
7647-01-0, 123-91-1
Purity
>=99%
Formula
C4HB802.HCL
Synonyms
1, 4 dioxane - Hydrochloride
Form
Liquid
Uses
• Anhydrous HCl source for moisture-sensitive reactions
• Salt formation of amines (HCl salts) in API synthesis
• Deprotection reactions (e.g., Boc, tert-butyl groups)
• Acid catalyst in organic synthesis under water-free conditions
• Activation of intermediates in fine chemicals and pharmaceutical processes
