(S)-(+) Glycidyl Phthalimide:
(S)-(+) Glycidyl Phthalimide, often abbreviated as G-Phthalimide, is a significant organic compound characterized by its chiral nature and functional groups. It is a derivative of phthalimide with a glycidyl group attached, exhibiting stereochemical specificity due to its chiral center. Its molecular formula is C10H7NO3.
Formula:
C11H9NO3
Synonyms of (S)-(+) Glycidyl Phthalimide:
- S)-2-OXIRANYLMETHYL-ISOINDOLE-1,3-DIONE
- (S)-N-Glycidylphthalimide
- 2-[[(2S)-oxiran-2-yl] methyl] isoindoline-1,3-dione
- 2-[(2S)-ox
- (S)-(+)-GL;2-Amino-8-picoline
- Rivaroxaban Impurity
- R;Linezolid EPP Impurity
(S)-(+) Glycidyl Phthalimide:
- Chirality : G-Phthalimide exists as a single enantiomer with the (S)-configuration, imparting stereochemical specificity to its interactions and reactions.
- Physical State : It typically appears as a white to off-white crystalline solid at room temperature.
- Solubility : G-Phthalimide exhibits limited solubility in water but is soluble in various organic solvents such as acetone, ethanol, and dichloromethane.
- Mekting Point : The melting point of G-Phthalimide ranges approximately from 140°C to 145°C.
- Purity : High-purity G-Phthalimide is essential for achieving desired results in synthetic and analytical applications.
What are the Applications of (S)-(+) Glycidyl Phthalimide:
G-Phthalimide serves as a valuable chiral building block in asymmetric synthesis, enabling the preparation of enantiomerically pure compounds with high stereochemical control.
Its epoxide functionality renders G-Phthalimide useful in various organic reactions, including ring-opening reactions, nucleophilic substitutions, and cycloadditions.
In polymer science, G-Phthalimide-containing monomers or polymer additives may impart specific properties such as chiral recognition, crosslinking, or functionalization.
In certain applications, IPA HCL is employed for surface treatment processes, modifying surface properties for improved adhesion or functionality.
G-Phthalimide derivatives have shown catalytic activity in certain transformations, acting as catalysts or ligands in asymmetric catalysis and metal-mediated reactions.
What are the Benefits of (S)-(+) Glycidyl Phthalimide:
Chirality and Selectivity
The chiral nature of G-Phthalimide enables precise control over stereochemistry in synthetic transformations, leading to the synthesis of enantiomerically enriched compounds.
Catalytic Activity
Certain G-Phthalimide derivatives exhibit catalytic activity, expanding their utility in asymmetric synthesis and catalysis.
Versatility
G-Phthalimide's functional groups offer versatility in organic synthesis, catalysis, and materials science, providing a platform for diverse applications.
Stereospecific Reactions
Its epoxide moiety enables stereospecific reactions, facilitating the construction of complex molecular architectures with defined stereochemistry.
What are the Safety Considerations for G-Phthalimide:
While G-Phthalimide offers significant potential in various applications, proper handling and safety precautions are essential:
Adequate ventilation should be maintained during handling to prevent inhalation of vapors.
Use of appropriate protective gear such as gloves, goggles, and lab coats is recommended to minimize exposure to skin or eyes.
G-Phthalimide should be stored in a cool, dry place away from sources of heat, light, or moisture to prevent degradation and ensure stability.
Care should be taken to avoid ingestion, inhalation, or direct contact with G-Phthalimide. In case of exposure, prompt rinsing with water and seeking medical attention is advised.
(S)-(+) Glycidyl Phthalimide stands as a testament to the power of stereochemistry in organic synthesis and catalysis, offering a versatile platform for innovation and discovery. Its unique properties, coupled with careful handling and adherence to safety protocols, pave the way for groundbreaking advancements in chemistry, materials science, and pharmaceutical research. Embrace the potential of G-Phthalimide to unlock new possibilities and shape the future of science and technology.
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